Biotechnology — Genes, CAR-T, Stem Cells & Biofoundries — Practice MCQs

Questions: 10 | Attempted: 0

Q1GS3moderate· statement correct

Consider the following statements regarding India's first gene-edited sheep:

Which of the statements given above is/are correct?

(A) 1 only(B) 2 only(C) 2 and 3 only(D) 1 and 3 only

Q2GS3easy· direct

Which of the following best describes BIRSA-101?

(A) India's first mRNA vaccine against malaria.(B) India's first indigenous CRISPR-based gene-editing therapy, developed for sickle cell disease.(C) A biofoundry under the BioE3 Policy located at CSIR-IGIB.(D) A genome-edited rice variety released by ICAR.

Q3GS3moderate· statement correct

With reference to India's regulation of gene-edited crops, consider the following statements:

Which of the statements given above are correct?

(A) 1 and 2 only(B) 2 and 3 only(C) 1 and 3 only(D) 1, 2 and 3

Q4GS3moderate· match pairs

Match List-I (Variety / product) with List-II (Developing institution):

List I

List II

Choose the correct match:

(A) Kamala–IIRR; Pusa DST–IARI; BIRSA-101–IGIB; NexCAR19–ImmunoACT(B) Kamala–IARI; Pusa DST–IIRR; BIRSA-101–ImmunoACT; NexCAR19–IGIB(C) Kamala–IIRR; Pusa DST–IARI; BIRSA-101–ImmunoACT; NexCAR19–IGIB(D) Kamala–IARI; Pusa DST–IIRR; BIRSA-101–IGIB; NexCAR19–ImmunoACT

Q5GS3easy· statement correct

Consider the following statements about CAR T-cell therapy:

Which of the statements given above are correct?

(A) 1 and 2 only(B) 2 and 3 only(C) 1 and 3 only(D) 1, 2 and 3

Q6GS3moderate· direct

A baby born through Mitochondrial Replacement Therapy is sometimes called a 'three-parent baby' because it carries genetic material from three sources. Which of the following best describes the source of nuclear DNA in such a baby?

(A) Nuclear DNA from the donor of healthy mitochondria, but no contribution from the prospective parents.(B) Nuclear DNA from the prospective father and mother; only the mitochondria come from a donor woman.(C) Nuclear DNA from the prospective mother and the donor; the father contributes only mitochondria.(D) Equal nuclear DNA contributions from the father, the prospective mother and the donor.

Q7GS3moderate· statement correct

With reference to the Phenome India National Biobank, consider the following statements:

Which of the statements given above are correct?

(A) 1 and 2 only(B) 2 and 3 only(C) 1 and 3 only(D) 1, 2 and 3

Q8GS3moderate· statement reason

Read the assertion (A) and reason (R) below:

Assertion (A): DRR Dhan 100 (Kamala) and Pusa DST Rice 1, India's new genome-edited rice varieties, have been released without going through the full regulatory process meant for genetically modified crops.

Reason (R): Both varieties involved Site Directed Nuclease (SDN) edits of category SDN-1 or SDN-2 in a general crop, which India's biosafety regulations have exempted from the strict GMO rules.

(A) Both A and R are true and R is the correct explanation of A.(B) Both A and R are true but R is not the correct explanation of A.(C) A is true but R is false.(D) A is false but R is true.

Q9GS3easy· direct

Which of the following best describes a 'biofoundry' as referenced in the National Biofoundry Network launched in 2025?

(A) A foundry that casts components for nuclear reactors using bio-mimicking materials.(B) An automated facility that designs, builds and tests engineered organisms by integrating DNA synthesis, gene editing and high-throughput biomanufacturing.(C) A subsidised loan window of the Reserve Bank of India for the biotechnology sector.(D) A WHO-recognised global directory of biotech researchers.

Q10GS3moderate· statement correct

Consider the following pairs of techniques and their core idea:

Which of the pairs given above are correctly matched?

(A) 1 and 2 only(B) 2 and 3 only(C) 1 and 3 only(D) 1, 2 and 3